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  • Title: Whither short-course chemotherapy for tuberculous meningitis?
    Author: Goel A, Pandya SK, Satoskar AR.
    Journal: Neurosurgery; 1990 Sep; 27(3):418-21. PubMed ID: 2234335.
    Abstract:
    Short-course chemotherapy is well established for the treatment of pulmonary tuberculosis but not for extrapulmonary disease. We present a series of 35 cases in which chemotherapy for tuberculous meningitis was given for a period of less than 2 years. Short-term therapy was associated with recrudescence of tuberculous meningitis and, in some cases, with the development of deep cerebral infarcts and permanent neurological deficits. We think short-term chemotherapy for tuberculosis of the central nervous system is inadequate.
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