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  • Title: New pentahydroxylated steroids from the South China Sea gorgonian Subergorgia suberosa.
    Author: Liao XJ, Tang LD, Liang YW, Jian SL, Xu SH, Liu YH.
    Journal: Chem Biodivers; 2012 Feb; 9(2):370-5. PubMed ID: 22344912.
    Abstract:
    Two new pentahydroxylated steroids, (3β,12β,16β,23E)-cholesta-5,23-diene-3,12,16,20,25-pentaol (1) and (3β,12β,16β)-cholesta-5,25(26)-diene-3,12,16,20,24-pentaol (2), were isolated from the EtOH extract of the South China Sea gorgonian Subergorgia suberosa. In addition, four known steroids were detected. The structures of these compounds were established by spectroscopic methods and comparison of their data with those of the related known compounds. In addition, the cyctotoxicities of the compounds were evaluated against selected cancer cell lines.
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