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  • Title: [Cellular function of microRNA-15 family].
    Author: Liu LF, Wang Y.
    Journal: Sheng Li Xue Bao; 2012 Feb 25; 64(1):101-6. PubMed ID: 22348968.
    Abstract:
    microRNAs (miRNAs) are non-coding endogenous short RNAs which are involved in regulating gene expression at the post-transcriptional level. miR-15 family is increasingly found to play great roles in important cell processes, such as apoptosis, cell differentiation and stress response. Growing evidence indicates that miR-15 family members are implicated in tumor, cardiovascular disease and neurodegenerative disease. miRNAs have emerged as a new promising subset of therapeutic targets. The present paper reviewed the important function of miR-15 family and new approaches for miRNA-based therapy.
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