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  • Title: [Effect of acute respiratory viral infection on the indicators of immunity in patients with pulmonary tuberculosis].
    Author: Kossiĭ NV, Gergert VIa, Abramova ZP.
    Journal: Probl Tuberk; 1990; (7):33-6. PubMed ID: 2235948.
    Abstract:
    To study the impact of acute respiratory viral infection (ARVI) on the course of pulmonary tuberculosis, 150 cases with this condition were under observation. These patients were divided into 2 groups: 88 subjects who had ARVI and 62 persons who did not have it, being in hospital. In the both groups those suffering from infiltrative and focal pulmonary tuberculosis were predominant. ARVI is conducive to the aggravation of a specific process in the lungs, which was registered in 27.3% of the cases who had had ARVI, and impede the reactions of cellular immunity to restore, which can be observed during chemotherapy. Among those who had ARVI, 68.4% of the patients demonstrated a decrease in T-cells and blast transformation with PHA. A significant drop in the number of T-lymphocytes and their functional activity, as a consequence of ARVI, promotes the deterioration of the above specific process. ARVI affects the efficacy of the in-patient treatment and decreases the proportion of patients with cavity closure.
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