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Title: Notch signaling: numb makes the difference. Author: Giebel B, Wodarz A. Journal: Curr Biol; 2012 Feb 21; 22(4):R133-5. PubMed ID: 22361152. Abstract: During Drosophila sensory organ precursor cell development, Numb segregates asymmetrically and functions as a cell fate determinant. Recent work now demonstrates in vivo that Numb inactivates Notch by promoting its endocytosis.[Abstract] [Full Text] [Related] [New Search]