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  • Title: [Pulmonary lymphangioleiomyomatosis. Radiologic aspects and the diagnostic role of computed tomography].
    Author: Zompatori M, Gavelli G, Schiavina M, Cornia B, Pileri S, Turci GA, Pisi P, Canini R.
    Journal: Radiol Med; 1990 Sep; 80(3):286-92. PubMed ID: 2236687.
    Abstract:
    Lymphangioleiomyomatosis (LAM) is an uncommon disease affecting women of reproductive capacity. It is characterized by non-neoplastic proliferation of smooth muscle in the lungs and, occasionally, in lymph nodes and in the thoracic duct. The patients present with dyspnea, chylous pleural effusion, pnx, and hemoptysis. The authors evaluated 4 patients with biopsy-proven LAM, by means of CT. In all cases, CT revealed small well-defined cystic air spaces with smooth and thin walls, scattered in the lungs. CT was very useful because it was more sensitive and specific than conventional radiography. The CT appearance of LAM distinctly differed from that of other diseases than can produce cystic air spaces in the lungs, such as UIP, eosinophilic granuloma, centri-acinar emphysema, and bronchiectasis. Our experience confirms the clinical usefulness of CT in diagnosing LAM.
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