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  • Title: [Activity of neutral peptide hydrolases and oxidative enzymes in the myocardium and blood during hypoxic hypoxia].
    Author: Ivashkevich AA, Man'kovskaia IN, Kurdanova AS.
    Journal: Ukr Biokhim Zh (1978); 1990; 62(4):55-60. PubMed ID: 2238155.
    Abstract:
    The citric cycle dehydrogenases and neutral peptide hydrolases (NPH) activity was determined in the myocardium and blood serum of Wistar rats under acute and prolonged hypoxic hypoxia. It was shown that the NPH activity and the activity of the most oxidative enzymes change in the same direction during adaptation to the high-altitude conditions. The role of the NPH in the oxidative metabolism reconstruction under acute and chronic hypoxia was discussed.
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