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  • Title: [The effect of hypoxic hypoxia on the activity of glycolysis enzymes in rat erythrocytes].
    Author: Sukhomlinov BF, Antoniak GL, Ikpu BO.
    Journal: Ukr Biokhim Zh (1978); 1990; 62(4):90-3. PubMed ID: 2238159.
    Abstract:
    The oxygen-binding properties of hemoglobin, concentration of 2,3-diphosphoglycerate, activity of carbohydrate metabolism enzymes and kinetics of rat erythrocyte hemolysis have been studied at high altitudes. The hemoglobin affinity to oxygen, glycolysis enzyme activity and erythrocyte membrane resistance are established to increase at the initial period of adaptation. The activation of the pentose-phosphate pathway of the glucose, transformation and inhibition of the glycolytic process in these cells are observed on the 10th day.
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