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Title: Advances in the treatment of pancreatic neuroendocrine tumours. Author: Gao F, Visvardis EE, Sita-Lumsden A, Waxman J. Journal: QJM; 2012 Sep; 105(9):819-22. PubMed ID: 22383691. Abstract: Pancreatic neuroendocrine tumours (pNETs) are relatively rare and generally felt to follow an indolent course. But poorly differentiated tumours can behave aggressively with 5-year survival ranging from 31% to 48%. Recent data suggest that patients with pNETs may derive benefit from treatment targeting the molecular changes expressed in this tumour group. This article describes advances in the treatment of unresectable pNETs that have led to a doubling of progression free survival.[Abstract] [Full Text] [Related] [New Search]