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  • Title: Salicylimine-based fluorescent chemosensor for aluminum ions and application to bioimaging.
    Author: Kim S, Noh JY, Kim KY, Kim JH, Kang HK, Nam SW, Kim SH, Park S, Kim C, Kim J.
    Journal: Inorg Chem; 2012 Mar 19; 51(6):3597-602. PubMed ID: 22385332.
    Abstract:
    In this study, an assay to quantify the presence of aluminum ions using a salicylimine-based receptor was developed utilizing turn-on fluorescence enhancement. Upon treatment with aluminum ions, the fluorescence of the sensor was enhanced at 510 nm due to formation of a 1:1 complex between the chemosensor and the aluminum ions at room temperature. As the concentration of Al(3+) was increased, the fluorescence gradually increased. Other metal ions, such as Na(+), Ag(+), K(+), Ca(2+), Mg(2+), Hg(2+), Mn(2+), Co(2+), Ni(2+), Cu(2+), Zn(2+), Cd(2+), Pb(2+), Cr(3+), Fe(3+), and In(3+), had no such significant effect on the fluorescence. In addition, we show that the probe could be used to map intracellular Al(3+) distribution in live cells by confocal microscopy.
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