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  • Title: Rhodium/copper-catalyzed annulation of benzimides with internal alkynes: indenone synthesis through sequential C-H and C-N cleavage.
    Author: Li BJ, Wang HY, Zhu QL, Shi ZJ.
    Journal: Angew Chem Int Ed Engl; 2012 Apr 16; 51(16):3948-52. PubMed ID: 22396146.
    Abstract:
    Doubled up: a rhodium(III)/copper(II) system co-catalyzes the annulation of benzimides with internal alkynes for the synthesis of indenones (see scheme; Cp*=C(5) Me(5)). The reaction involves an uncommon nucleophilic addition of a transition-metal-carbon bond to an imide moiety. This novel reaction provides a facile route to synthesize indenones from readily available benzimides and internal alkynes.
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