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  • Title: Membranous nephropathy associated with giant lymph node hyperplasia. A case report with histological and ultrastructural studies.
    Author: Ruggieri G, Barsotti P, Coppola G, Spinelli C, Balducci A, Ventola FR, d'Adamo G, Tata MV, Marinozzi V.
    Journal: Am J Nephrol; 1990; 10(4):323-8. PubMed ID: 2240060.
    Abstract:
    A young woman presented with nephrotic syndrome due to membranous nephropathy and a localized form of giant lymph node hyperplasia (Castleman's disease) occurring as a large intra-abdominal mass. Five months after surgical removal of the mass, only mild proteinuria persisted. Twenty months later a second kidney biopsy showed a near-normal morphology. Six years later the patient was free of symptoms and had normal urinalysis. Reviewing the pertinent literature, it seems to be the first case of a biopsy-proven cure of membranous nephropathy in a patient with membranous nephropathy and Castleman's disease.
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