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  • Title: Quality of life among liver transplantation patients.
    Author: Sirivatanauksorn Y, Dumronggittigule W, Limsrichamrern S, Iramaneerat C, Kolladarungkri T, Kositamongkol P, Mahawithitwong P, Asavakarn S, Tovikkai C.
    Journal: Transplant Proc; 2012 Mar; 44(2):532-8. PubMed ID: 22410064.
    Abstract:
    BACKGROUND: Orthotopic liver transplantation (OLT) is the treatment of choice for end-stage disease. It offers a chance to return to an active and prolonged life. Recently, more attention is being paid to the health-related quality of life (HRQoL) of patients and their spouses or caregivers after OLT. The aim of this study was to analyze the pre- versus posttransplantation HRQoL of patients and their spouses or caregivers using generic and disease-specific health questionnaires. MATERIAL AND METHODS: The study was performed between October 2010 and January 2011 using the Short Form-36 (SF-36) and the Chronic Liver Disease Questionnaire (CLDQ) to evaluate the HRQoL. RESULTS: Posttransplantation patients (N=59, mean age 53.39 [range, 23 to 76] years, male 63.2%, female 36.8%) and their spouses and caregivers showed significantly better generic SF-36 HRQoL scores, namely, physical and social functioning, role limitations because of physical or emotional problems, bodily pain, vitality, as well as general and mental health compared with pretransplantation patients (N=57, mean age 54.56 (range, 22 to 69) years, male 71.2%, female 28.8%). Similarly, the posttransplantation group showed significantly improved CLDQ scores in all domains: fatigue, activity, abdominal symptoms, systemic symptoms, emotional function, and worry. CONCLUSION: OLT improved HRQoL of end-stage liver patients and their spouses or caregivers.
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