These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Working condition: A key factor in increasing occupational hazard among bidi rollers: A population health research with respect to DNA damage.
    Author: Shukla P, Khanna A, Jain SK.
    Journal: Indian J Occup Environ Med; 2011 Sep; 15(3):139-41. PubMed ID: 22412294.
    Abstract:
    The present investigation was undertaken to study the role of working conditions in occupational hazards among bidi rollers occupationally exposed to tobacco dust with reference to DNA damage in peripheral blood lymphocytes. Initially, biomonitoring was conducted by estimating urinary thioether to detect the extent of xenobiotic exposure, and genotoxicity was evaluated by assessing DNA damage and micronucleus frequency in buccal epithelial cells in female bidi rollers occupationally exposed to bidi tobacco dust. Student's t-test was used to test the significance between the means. Results showed a significant increase in urinary thioether level in during-shift urine samples as compared to pre-shift samples, which indicated exposure of bidi rollers to xenobiotic compounds. A significant increase in DNA damage was observed in the rollers working in confined environment as compared to those who worked in open and mixed kind of working conditions. Keeping in view the adverse effects of tobacco inhalation on the genotoxic effects in bidi rollers as an occupational hazard and in order to minimize the hazardous effects, it is recommended that masks should be worn by the bidi rollers during work to minimize inhalation of tobacco dust. Gloves should be worn particularly if there are bruises etc. in the palm. To minimize the absorption through eyes, covered glasses should be worn. The entire process of bidi rolling may be done preferably under well ventilated conditions. Due care to be taken to sit in the direction facing the direction of wind to avoid inhalation of blown away tobacco dust.
    [Abstract] [Full Text] [Related] [New Search]