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  • Title: Lack of effect of acid-base alterations on growth hormone secretion in man.
    Author: Klimes I, Vigas M, Jurcovicová J, Németh S.
    Journal: Endocrinol Exp; 1977 Sep; 11(3):155-62. PubMed ID: 22432.
    Abstract:
    In order to study the possible effect of acid-base alterations on growth hormone (GH) secretion in man the exercise-induced GH secretion was compared with the tentative GH release resulting from the acidosis due to hyperlactacidemia after the infusion of fructose. Submaximal exercise on bicycle ergometer resulted in a significant increase of plasma GH and lactate and in acid-base alterations. The infusion of 60 g of fructose during 60 min was without effect on plasma GH level in spite of the increase of serum lactate and slight acid-base alterations. It is concluded that no causal relationship may be found between the acid-base alterations and the increase of plasma GH during physical exercise.
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