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  • Title: A high-flux isopore micro-fabricated membrane for effective concentration and recovering of waterborne pathogens.
    Author: Warkiani ME, Lou CP, Liu HB, Gong HQ.
    Journal: Biomed Microdevices; 2012 Aug; 14(4):669-77. PubMed ID: 22441820.
    Abstract:
    A high-flux metallic micro/nano-filtration membrane has been fabricated and validated for isolation of waterborne pathogens from drinking water. Obtained membrane with smooth surface and perfectly ordered pores was achieved by a high yield and cost effective multilevel lithography and electroplating technique. The micro-fabricated membrane was also strengthened with an integrated back-support, which can withstand a high pressure during filtration. The results of microfiltration tests with model particles revealed the superior performance of the micro-fabricated filter than current commercial filters in sample throughput, recovery ratio, and reusability. This study highlighted the potential application of micro-fabricated filer in rapid filtration and recovery of C. parvum oocysts for downstream analysis.
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