These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Modulation of the blood-stimulating effect of immobilized granulocyte colony-stimulating factor by immobilized hyaluronidase.
    Author: Dygai AM, Zhdanov VV, Zyuz'kov GN, Udut EV, Khrichkova TY, Simanina EV, Stavrova LA, Miroshnichenko LA, Chaikovskii AV, Markova TS, Gurto RV, Artamonov AV, Bekarev AA, Madonov PG.
    Journal: Bull Exp Biol Med; 2011 Jul; 151(3):324-9. PubMed ID: 22451878.
    Abstract:
    We evaluated whether immobilized hyaluronidase can modify the hematotropic effect of immobilized granulocyte CSF (G-CSF). The preparation of immobilized hyaluronidase (50 arb. units per mouse) potentiated the specific effect of immobilized G-CSF on granulomonocytopoiesis. The preparation was shown to facilitate the indirect effect of immobilized G-CSF on hemopoiesis (stimulation of the erythroid and lymphoid hemopoietic stems). These changes were accompanied by an increase in functional activity of hemopoietic precursor cells, secretion of humoral factors by bone marrow myelokaryocytes, and concentration of hemopoietins in the serum.
    [Abstract] [Full Text] [Related] [New Search]