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  • Title: A label-free fluorescence DNA probe based on ligation reaction with quadruplex formation for highly sensitive and selective detection of nicotinamide adenine dinucleotide.
    Author: Zhao J, Zhang L, Jiang J, Shen G, Yu R.
    Journal: Chem Commun (Camb); 2012 May 11; 48(37):4468-70. PubMed ID: 22456321.
    Abstract:
    A simple label-free fluorescent sensing scheme for sensitive and selective detection of nicotinamide adenine dinucleotide (NAD(+)) has been developed based on DNA ligation reaction with ligand-responsive quadruplex formation. This approach can detect 0.5 nM NAD(+) with high selectivity against other NAD(+) analogs.
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