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  • Title: Tumor necrosis factor-α inhibitor use is not associated with lipid changes in rheumatoid arthritis.
    Author: Bili A, Morris SJ, Sartorius JA, Kirchner HL, Antohe JL, Dancea S, Wasko MC.
    Journal: J Rheumatol; 2012 May; 39(5):946-8. PubMed ID: 22467937.
    Abstract:
    OBJECTIVE: To determine the association of use of tumor necrosis factor-α (TNF-α) inhibitors with differences in lipid levels in patients with rheumatoid arthritis (RA). METHODS: We studied 807 patients with incident RA to compare differences in lipid levels in TNF-α inhibitor users versus nonusers, with adjustment for relevant covariables. RESULTS: TNF-α inhibitor use was not associated with differences in levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), triglycerides, LDL:HDL, or TC:HDL compared to nonusers. CONCLUSION: Use of TNF-α inhibitor was not associated with differences in lipid levels in patients with RA.
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