These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter.
    Author: Lum LS, Sultzman LA, Kaufman RJ, Linzer DI, Wu BJ.
    Journal: Mol Cell Biol; 1990 Dec; 10(12):6709-17. PubMed ID: 2247079.
    Abstract:
    The basal promoter of the human hsp70 gene is predominantly controlled by a CCAAT element at position -70 relative to the transcriptional initiation site. We report the isolation of a novel cDNA clone encoding a 114-kDa polypeptide that binds to the CCAAT element of the hsp70 promoter. Expression of this CCAAT-binding factor (CBF) cDNA activated transcription from cotransfected hsp70 promoter-reporter gene constructs in a CCAAT-dependent manner. CCAAT-binding factor shows no homology to the previously identified human CCAAT transcription factor or rat CCAAT/enhancer-binding protein.
    [Abstract] [Full Text] [Related] [New Search]