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  • Title: Evaluation of clinical aspects and quality of life as risk factors for depression in patients with epilepsy.
    Author: Zhao T, Sun MY, Yu PM, Zhu GX, Tang XH, Shi YB, Hong Z.
    Journal: Seizure; 2012 Jun; 21(5):367-70. PubMed ID: 22472268.
    Abstract:
    The purpose of this study was to investigate clinical aspects and quality of life (QOL) as risk factors for depression in patients with epilepsy. One hundred and forty outpatients with a diagnosis of epilepsy who were attending our epilepsy center participated. Patients anonymously filled out a questionnaire with clinical data related to epilepsy. Depression level was evaluated by the Hamilton Depression Rating Scale-17 (HAMD-17), and quality of life was evaluated by the Quality of Life in Epilepsy-31 (QOLIE-31). Thirty-six patients with epilepsy suffered from depression (25.7%). Complex partial seizures (OR=0.112) and number of seizure types (OR=3.773) were found to be clinical risk factors for depression. Low scores for seizure worry (OR=0.947) and social function (OR=0.947) on the QOLIE-31 increased the probability of depression in patients with epilepsy.
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