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  • Title: Moclobemide (Ro 11-1163) versus imipramine in the treatment of depression.
    Author: Casacchia M, Moll E.
    Journal: Acta Psychiatr Scand Suppl; 1990; 360():43. PubMed ID: 2248067.
    Abstract:
    Moclobemide and imipramine were compared single-blind in 2 groups of 20 depressed patients (75% and 65% endogenous depression respectively). There was no significant difference between the 2 groups in improvement on the Hamilton Rating Scale for Depression. The final overall assessment of efficacy was good or very good in 80% of the moclobemide patients and 55% on imipramine. Tolerance was good to very good in 95% of moclobemide patients, compared with 80% on imipramine. No severe adverse effects were reported in either group.
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