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  • Title: Comparison of four local extradural anaesthetic solutions for elective caesarean section.
    Author: Howell P, Davies W, Wrigley M, Tan P, Morgan B.
    Journal: Br J Anaesth; 1990 Nov; 65(5):648-53. PubMed ID: 2248843.
    Abstract:
    We have examined a combination of two local anaesthetics to see if the resultant solution is superior to the agents individually. This study shows that a mixture of bupivacaine and lignocaine provided an excellent alternative to bupivacaine alone, and was superior to 2% lignocaine with adrenaline for elective Caesarean section. By reducing the dose of bupivacaine used, the combination may reduce the risk of cardiotoxicity.
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