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  • Title: [Quadratic regression-orthogonal design optimization ethanol extraction craft of baicalin].
    Author: Shi L, Zhang ZW.
    Journal: Zhong Yao Cai; 2011 Dec; 34(12):1946-50. PubMed ID: 22500436.
    Abstract:
    OBJECTIVE: To optimize the extraction process of baicalin using the quadratic regression-orthogonal design. METHODS: The influential factors were ethanol doses, ethanol concentration and extract time. Used the high level statistical method to design experiment parameter and forecast analysis results. RESULTS: The optimization conditions of extraction was 64% ethanol, 115 min for extract time,volume of use 11. 6 times and it's extraction rate was 85.21%. CONCLUSION: It shows that the optimum model is simple,highly precision and highly predictive.
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