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  • Title: Erythema nodosum-like lesions in Behçet's disease: a clinicopathological study of 26 cases.
    Author: Misago N, Tada Y, Koarada S, Narisawa Y.
    Journal: Acta Derm Venereol; 2012 Nov; 92(6):681-6. PubMed ID: 22504656.
    Abstract:
    The histopathological features of erythema nodosum-like lesions remain controversial with regard to whether they resemble those of conventional erythema nodosum. We reviewed the clinicopathological features of erythema nodosum-like lesions in 26 patients with Behçet's disease and evaluated the clinical characteristics of Behçet's disease in these patients. The results suggest that: (i) the clinico-pathological features of 27% of the erythema nodosum-like lesions in Behçet's disease are indistinguishable from those of conventional erythema nodosum; (ii) the other 73% of the erythema nodosum-like lesions are histopathologically characterized by the presence of vasculitis (venulitis or phlebitis); (iii) the clinical features of erythema nodosum-like lesions with vasculitis show heterogeneity; (iv) the presence of the erythema nodosum type lesion may be an indicator of the mildness of Behçet's disease; and (v) the presence of severe vasculitis, especially phlebitis, in erythema nodosum-like lesions may be an indicator of the involvement of the gastrointestinal tract in Behçet's disease.
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