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  • Title: Alopecia with perineural lymphocytes: a clue to linear scleroderma en coup de sabre.
    Author: Goh C, Biswas A, Goldberg LJ.
    Journal: J Cutan Pathol; 2012 May; 39(5):518-20. PubMed ID: 22515223.
    Abstract:
    Linear scleroderma en coup de sabre ('the stroke of the sword') is an uncommon form of morphea with onset typically in childhood or adolescence. Involvement is usually located on the paramedian forehead and is associated with alopecia. It is microscopically indistinguishable from other forms of scleroderma. We present a 51-year-old woman who presented with alopecia and subsequently developed linear scleroderma en coup de sabre on her adjacent forehead. Histopathology revealed a strikingly perineural lymphocytic and plasmacytic infiltrate, extending deeply into the subcutis and fascia. To our knowledge, this is the first report of alopecia with perineural lymphocytic inflammation as a presenting sign of linear scleroderma en coup de sabre.
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