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Title: Immunohistochemical characterization of perineal melanoma in Kilis goats. Author: Ozyildiz Z, Ceylan C, Yilmaz R, Ozsoy SY. Journal: Biotech Histochem; 2012 Aug; 87(6):408-12. PubMed ID: 22519426. Abstract: We describe the clinical, histopathological and immunohistochemical features of the malignant melanomas in the perineal regions of Kilis goats from Sanliurfa province in Turkey. We studied 13 female Kilis goats between 3 and 8 years old that were brought to Harran University Veterinary School, Department of Surgery, between 2002 and 2010. By macroscopic examination, the masses were determined to have elastic consistency, dark brown-black color, necrotic surfaces and ulceration. Microscopically, pleomorphic cells were observed under the basal layer and these advanced toward the dermis. These cells were polyhedral, round or spindle-shaped, anaplastic, and their cytoplasm contained varying amounts of dark brown-black pigments. Immunohistochemical staining was obtained with anti-melan A, vimentin and S100 antibodies.[Abstract] [Full Text] [Related] [New Search]