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  • Title: Cytotoxic activity of some glycoconjugates including saponins and anthracyclines.
    Author: Ekholm FS, Berényi Á, Lagerquist L, Saloranta T, Zupkó I, Schneider G, Wölfling J, Leino R.
    Journal: Carbohydr Res; 2012 Jul 15; 356():295-8. PubMed ID: 22520504.
    Abstract:
    Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed.
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