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  • Title: Domino cyclization-alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols.
    Author: Xu C, Murugan VK, Pullarkat SA.
    Journal: Org Biomol Chem; 2012 May 21; 10(19):3875-81. PubMed ID: 22526600.
    Abstract:
    A practical and efficient protocol for the one-pot synthesis of 2,3-substituted indoles was developed via a palladacycle catalyzed domino cyclization-alkylation reaction involving 2-alkynylanilines and allylic alcohols under mild conditions without any additives.
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