These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Isolation, identification, semi-synthesis of aziditaxel derivatives and their biological evaluation.
    Author: Zhang SE, Tao JY, Zhao Y, Wang SR, Zhou D, Fang WS.
    Journal: J Asian Nat Prod Res; 2012; 14(5):463-75. PubMed ID: 22530674.
    Abstract:
    Two new taxoids (5 and 6) were obtained by isolating impurities in aziditaxel, and their structures were characterized based on data analysis of (1)H NMR, (13)C NMR, HPLC-MS, and through comparison with literature. In order to test their cytotoxicities against human nonsmall lung cancer cell lines (A549), sufficient amounts of compounds 5 and 6 were obtained by semi-synthesis and both of them showed equipotent cytotoxiesty compared with taxol, docetaxel, and aziditaxel.
    [Abstract] [Full Text] [Related] [New Search]