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  • Title: Dose dependent enzyme induction by oxcarbazepine?
    Author: Patsalos PN, Zakrzewska JM, Elyas AA.
    Journal: Eur J Clin Pharmacol; 1990; 39(2):187-8. PubMed ID: 2253672.
    Abstract:
    Antipyrine half life and clearance was compared in four patients with classical idiopathic trigeminal neuralgia during carbamazepine (CBZ) or CBZ/phenytoin (PHT) and after substitution with oxcarbazepine (OXC) monotherapy. OXC is observed to be less of a hepatic enzyme inducer than CBZ or CBZ/PHT in combination, however induction by OXC may be dose related.
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