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  • Title: Innate immunity's path to the Nobel Prize 2011 and beyond.
    Author: Wagner H.
    Journal: Eur J Immunol; 2012 May; 42(5):1089-92. PubMed ID: 22539282.
    Abstract:
    The 2011 Nobel Prize in Physiology/Medicine to Ralph Steinmann, Jules Hoffmann, and Bruce Beutler recognized a paradigm shift in our understanding of innate immunity, and its impact on adaptive immunity. The Prize highlighted the initial discoveries of Toll's role in immunity in flies, Toll-like receptors in mammals, and the establishment of dendritic cells as the initiators of adaptive immunity. This historical Commentary focuses on the developments in our understanding of innate immunity.
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