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  • Title: A clinical contribution to guideline criteria in the excision of pigmentary lesions.
    Author: Dal Pozzo V, Podenzani S, Cavicchini S.
    Journal: G Ital Dermatol Venereol; 1990 May; 125(5):173-7. PubMed ID: 2253946.
    Abstract:
    The clinical diagnosis of cutaneous melanoma is often difficult at the first stages of the malignant proliferation. The proposed anamnestic and clinical guidelines can offer useful criteria for the majority of the cases but sometimes a preventive excision is required for lesions that only partially fulfill the classic markers of "at risk" lesions. In this paper based on a comparative study between 2000 pigmented lesions and 40 melanomas of uncertain clinical diagnosis, the Authors recognize 5 statistically significant clinical pattern of benign pigmented lesions undistinguishable from clinically unusual melanomas. Epidemiological data about sex and age of the patients, histologically classification, site of the pigmented lesions and malignant transformation of congenital nevi are also reported.
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