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  • Title: Mesothelioma associated with commercial use of vermiculite containing Libby amphibole.
    Author: Dunning KK, Adjei S, Levin L, Rohs AM, Hilbert T, Borton E, Kapil V, Rice C, Lemasters GK, Lockey JE.
    Journal: J Occup Environ Med; 2012 Nov; 54(11):1359-63. PubMed ID: 22544163.
    Abstract:
    OBJECTIVES: To describe asbestos-related mortality among manufacturing workers who expanded and processed Libby vermiculite that contained amphibole fiber. METHODS: Standardized mortality ratio was calculated for 465 white male workers 31 years after last Libby vermiculite exposure. RESULTS: Two workers died from mesothelioma, resulting in a significantly increased standardized mortality ratio of 10.5 (95% confidence interval, 1.3 to 38.0). These workers were in the upper 10th percentile of cumulative fiber exposure, that is, 43.80 and 47.23 fiber-years/cm, respectively. One additional worker with cumulative fiber exposure of 5.73 fiber-years/cm developed mesothelioma but is not deceased. There were no other significantly increased standardized mortality ratios. CONCLUSIONS: Workers expanding and processing Libby vermiculite in a manufacturing setting demonstrated an increased risk for the development of mesothelioma following exposure to the amphibole fiber contained within this vermiculite ore source.
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