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  • Title: [The use of apressin in patients with pulmonary tuberculosis and functional disorders of the external respiration and hemodynamics].
    Author: Mar'iandyshev AO, Tikhonov VA, Evsraf'ev IuA, Grigor'ev IuG.
    Journal: Probl Tuberk; 1990; (8):32-4. PubMed ID: 2255693.
    Abstract:
    Effects of apressin, a peripheral vasodilator, on external respiration function and central hemodynamics was studied in 51 patients with pulmonary tuberculosis. The study showed that a single administration of 20 mg apressin in pulmonary tuberculosis patients failed to bring about any changes in both external respiration function and blood gases, only causing a minor shift in the buffer bases. Systolic pressure in the pulmonary artery remained unchanged after a single 20 mg dose of apressin was given. A statistically significant decrease in total pulmonary vascular resistance and an increase of the central hemodynamic values in pulmonary tuberculosis patients with hypokinetic type of circulation are recorded.
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