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Title: Reproductive behaviour of mothers of children with beta-thalassaemia major. Author: Habibzadeh F, Yadollahie M, Roshanipoor M, Haghshenas M. Journal: East Mediterr Health J; 2012 Mar; 18(3):246-9. PubMed ID: 22574478. Abstract: Thalassaemia is the most common monogenic autosomal hereditary disease worldwide. This questionnaire-based cross-sectional study looked at the reproductive behaviour of 156 mothers of children affected with beta-thalassaemia major (Cooley anaemia) in Fars province, southern Islamic Republic of Iran. Regardless of the number of affected children, the parents of children with Cooley anaemia had an average of 3 unaffected children, the same as the average for the provincial population. The findings indicate that reproductive compensation occurs in families with a child with Cooley anaemia in this province. Genetic counselling, either before marriage or after the birth of the first affected child, had a significant effect on lowering the number of children born.[Abstract] [Full Text] [Related] [New Search]