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  • Title: Anticonvulsant action of an arylamine-containing fraction from Agelenopsis spider venom.
    Author: Jackson H, Parks TN.
    Journal: Brain Res; 1990 Sep 03; 526(2):338-41. PubMed ID: 2257489.
    Abstract:
    A low molecular weight fraction (AG2) containing arylamine compounds has been isolated from venom of the spider Agelenopsis aperta. When administered intravenously or intracerebroventricularly, AG2 produces dose-dependent suppression of behavioral convulsions induced in rats by kainic acid, picrotoxin, or bicuculline. The low molecular weight compounds in spider venoms may provide novel tools for anticonvulsant research and therapy.
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