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  • Title: Relation between indices of end-organ damage and mean platelet volume in hypertensive patients.
    Author: Bulur S, Önder HI, Aslantas Y, Ekinozu I, Kiliç AÇ, Yalcin S, Bulur Ş, Ozhan H.
    Journal: Blood Coagul Fibrinolysis; 2012 Jul; 23(5):367-9. PubMed ID: 22576288.
    Abstract:
    Mean platelet volume (MPV) has been recognized as an independent risk factor of hypertension. Hypertensive end-organ damage worsens the prognosis in hypertensive patients. We aimed to investigate the relationship between MPV levels and subclinical end-organ damage in hypertensive patients. One hundred and sixteen hypertensive patients (81 women, 35 men, with a mean age of 53 ± 11) were included in the study. There was no correlation between MPV and left-ventricular mass index (LVMI) (r = 0.145; P = 0.14) or albuminuria (r = 0.009; P = 0.93). Among the individuals that had grade I and grade II retinopathy, MPV levels (8.3 ± 2 fL, 8.2 ± 1.3 fL; P = 0.28) were similar either. We concluded that there was no correlation between MPV and markers of end-organ damage in hypertensive patients.
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