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  • Title: [A case of disseminated carcinomatosis of bone marrow treated by S-1 and cisplatin after distal gastrectomy for early gastric cancer].
    Author: Tsuji K, Doyama H, Yamada S, Kaneko Y, Takemura K, Tsuji S, Tominaga K, Inagaki S, Hayashi T, Ito R, Nakanishi H, Kitou Y, Takeda Y, Yamamoto M, Inaki N, Yamada T, Niwa H, Katayanagi K, Kurumaya H.
    Journal: Gan To Kagaku Ryoho; 2012 May; 39(5):813-5. PubMed ID: 22584338.
    Abstract:
    Patients with bone metastasis originating from gastric cancer experience complications from DIC. They are treated with anticoagulation therapy or platelet transfusion, but their prognosis is poor. Our case was a 50-year-old male who had undergone distal gastrectomy for early gastric cancer[pT1a(M)N0M0, pStage I a]ten years previously. He was admitted to our hospital complaining of backache. As a result of his examination, he was diagnosed with disseminated carcinosis of bone marrow with DIC as a postoperative recurrence of gastric cancer. The patient was treated with combination chemotherapy of S-1 and cisplatin(S-1 80 mg/body, po, day 1-21 and cisplatin 50mg/body, iv, day 8). After one course of treatment, DIC was resolved and his pain was relieved. He survived for about nine months. S-1 and cisplatin are considered to be effective for disseminated carcinosis of bone marrow.
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