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  • Title: An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines.
    Author: Parmar NJ, Pansuriya BR, Barad HA, Kant R, Gupta VK.
    Journal: Bioorg Med Chem Lett; 2012 Jun 15; 22(12):4075-9. PubMed ID: 22607678.
    Abstract:
    An improved microwave assisted one-pot method for the synthesis of twelve new aryldiazenylchromeno [4,3-b] pyrrolidines via intramolecular azomethine ylide cycloaddition route is described. The method is efficient and advantageous over conventional and solvent-free thermal methods. The stereochemistry of the compounds was confirmed on the basis of various NMR experiments, and finally by single crystal X-ray diffraction data. N-Methyl or ethyl pyrrolidine based heterocycles gave good biological activities.
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