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  • Title: [Effects of baicalin and liquid extract of licorice on sorbitol level in red blood cells of diabetic rats].
    Author: Zhou Y, Zhang J.
    Journal: Zhongguo Zhong Yao Za Zhi; 1990 Jul; 15(7):433-5, 448. PubMed ID: 2261079.
    Abstract:
    10 streptozotocin-induced diabetic rats were treated with baicalin 150 mg/kg.d and liquid extract of licorice (LEL) 7.5 ml/kg.d (5 by each medicine) for a week. The results indicated that orally baicalin and LEL could dramatically reduce the sorbitol levels in red blood cells (123.7 +/- 28.6 to 72.5 +/- 21.8 and 116.9 +/- 25.2 to 80.5 +/- 23.8 nmol/g.Hb, respectively) without affecting blood glucose levels significantly. It is suggested that both medicines act by inhibiting aldose reductase.
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