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  • Title: Sarcocrassocolides M-O, bioactive cembranoids from the Dongsha Atoll soft coral Sarcophyton crassocaule.
    Author: Lin WY, Lu Y, Chen BW, Huang CY, Su JH, Wen ZH, Dai CF, Kuo YH, Sheu JH.
    Journal: Mar Drugs; 2012 Mar; 10(3):617-626. PubMed ID: 22611358.
    Abstract:
    Three new cembranoids, sarcocrassocolides M-O (1-3), have been isolated from the soft coral Sarcophyton crassocaule. The structures of the metabolites were determined by extensive spectroscopic analysis. Compounds 1-3 were shown to exhibit moderate cytotoxicity toward a limited panel of cancer cell lines and display significant in vitro anti-inflammatory activity in LPS-stimulated RAW264.7 macrophage cells by inhibiting the expression of the iNOS protein.
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