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  • Title: The use of precut, γ-irradiated corneal lenticules in Boston type 1 keratoprosthesis implantation.
    Author: Akpek EK, Aldave AJ, Aquavella JV.
    Journal: Am J Ophthalmol; 2012 Sep; 154(3):495-498.e1. PubMed ID: 22633353.
    Abstract:
    PURPOSE: To report the use of a sterile, γ-irradiated corneal tissue without viable endothelium (VisionGraft Sterile Cornea; Tissue Banks International) in lieu of fresh donor cornea in Boston type 1 keratoprosthesis (KPro) implantation. DESIGN: Retrospective, interventional small case series. METHODS: Eleven eyes of 11 patients underwent Boston type 1 keratoprosthesis implantation using VisionGraft Sterile Cornea between April 2009 and October 2010. Precut donut-shaped corneal lenticules, using femtosecond laser, measuring 8.5 mm in diameter with a 3-mm central hole were used. RESULTS: Surgical procedures were uneventful. Complete corneal re-epithelization was noted within 10 days in all cases. No complications related to the donor cornea (eg, stromal necrosis, wound leak, or device extrusion) occurred over an average follow-up of 16.5 months. CONCLUSIONS: VisionGraft Sterile Cornea eliminates the need for use of fresh donor corneal tissue for Boston type 1 keratoprosthesis procedures, which makes this procedure a viable sight-restoring option when donor corneal tissues are not readily available.
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