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  • Title: Preparation of quinolinium salts differing in the length of the alkyl side chain.
    Author: Marek J, Buchta V, Soukup O, Stodulka P, Cabal J, Ghosh KK, Musilek K, Kuca K.
    Journal: Molecules; 2012 May 25; 17(6):6386-94. PubMed ID: 22634846.
    Abstract:
    Quaternary quinolinium salts differing in alkyl chain length are members of a widespread group of cationic surfactants. These compounds have numerous applications in various branches of industry and research. In this work, the preparation of quinoline-derived cationic surface active agents differing in the length of the side alkyl chains (from C₈ to C₂₀) is described. An HPLC method was successfully developed for distinction of all members of the series of prepared long-chain quinolinium derivatives. In conclusion, some possibilities of intended tests or usage have been summarized. In vitro testing using a microdilution broth method showed good activity of a substance with a C12 chain length against Gram-positive cocci and Candida species.
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