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  • Title: [Fatal haemophagocytic lymphohistiocytosis and mononucleosis in a patient with colitis ulcerosa].
    Author: Ingvardsen CJ, Ballegaard VC, Homøe P.
    Journal: Ugeskr Laeger; 2012 May 21; 174(21):1461-2. PubMed ID: 22640789.
    Abstract:
    We report a case of Epstein-Barr virus primo infection with the development of lethal haemophagocytic lymphohistiocytosis (HLH) in a 22 year-old man, who was being treated with azathioprin for colitis ulcerosa. HLH is a rare, life-threatening disease, which is caused by an inappropriate activation of the immune system with haemophagocytosis and multiorgan system dysfunction. Early initiation of treatment significantly improves survival.
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