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  • Title: [Adrenergic regulation of thermogenesis in Siberian lemmings].
    Author: Pastukhov IuF, Belogubova EG, Valov RP.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1979 Sep; 65(9):1340-5. PubMed ID: 226423.
    Abstract:
    Siberian lemmings seem to have lesser noradrenaline (NA) calorigenic action and higher beta-adrenergic "asymmetry" of catecholamine calorigenic effects than the cold- and warmth-adapted laboratory rodents. Selective inhibition of catecholamine effects by beta-adrenoblocking drug propranolol, obvious potentiation of NA effect by caffeine, and compensatory increasing of thermoregulatory musclar contractile activity during the blockade of betaadrenoreceptors under cooling suggest the domineering of betaadrenergic mechanisms of thermogenesis in siberian lemmings and their high thermoregulatory lability.
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