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  • Title: Prolonged preservation of cadaver heart with Belzer UW solution: 24-hour storage system for asphyxiated canine hearts.
    Author: Shirakura R, Matsuda H, Nakata S, Kaneko M, Kawaguchi A, Miyagawa S, Fukushima N, Kitagawa S, Naka Y, Kawashima Y.
    Journal: Eur Surg Res; 1990; 22(4):197-205. PubMed ID: 2265654.
    Abstract:
    The efficacy of Belzer UW solution was compared to Collins' solution in the preservation of asphyxiated cadaver hearts in a canine model. Donor hearts were stored for 24 h: 2 h of in situ hypothermic (15 degrees C) coronary perfusion plus 22 h of simple immersion in ice-cold solution. Verapamil, propranolol and prostacyclin were used for myocytoprotection in both groups. After orthotopic transplantation, all animals were weaned off bypass without inotropic support. After 1 h, however, the cardiac output was significantly higher in the Belzer UW solution group (128 +/- 28 vs. 67 +/- 13 ml/kg/min, p less than 0.01).
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