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  • Title: Platelet monoamine oxidase B activity in parkinsonian patients.
    Author: Bonuccelli U, Piccini P, Del Dotto P, Pacifici GM, Corsini GU, Muratorio A.
    Journal: J Neurol Neurosurg Psychiatry; 1990 Oct; 53(10):854-5. PubMed ID: 2266365.
    Abstract:
    Monoamine oxidase B (MAO B) plays a pivotal role in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced Parkinsonism. An increased MAO B activity in platelets of patients with idiopathic Parkinson's disease (PD) is reported in this study. The possibility that high MAO B activity may represent a trait of vulnerability for PD by enhancing the neurotoxic effects of environmental compounds is discussed.
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