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  • Title: Destructive discovertebral degenerative disease of the lumbar spine.
    Author: Charran AK, Tony G, Lalam R, Tyrrell PN, Tins B, Singh J, Eisenstein SM, Balain B, Trivedi JM, Cassar-Pullicino VN.
    Journal: Skeletal Radiol; 2012 Sep; 41(10):1213-21. PubMed ID: 22664859.
    Abstract:
    The uncommon variant of degenerative hip joint disease, termed rapidly progressive osteoarthritis, and highlighted by severe joint space loss and osteochondral disintegration, is well established. We present a similar unusual subset in the lumbar spine termed destructive discovertebral degenerative disease (DDDD) with radiological features of vertebral malalignment, severe disc resorption, and "bone sand" formation secondary to vertebral fragmentation. Co-existing metabolic bone disease is likely to promote the development of DDDD of the lumbar spine, which presents with back pain and sciatica due to nerve root compression by the "bone sand" in the epidural space. MRI and CT play a complimentary role in making the diagnosis.
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