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  • Title: Tudor domain proteins in development.
    Author: Pek JW, Anand A, Kai T.
    Journal: Development; 2012 Jul; 139(13):2255-66. PubMed ID: 22669818.
    Abstract:
    Tudor domain proteins function as molecular adaptors, binding methylated arginine or lysine residues on their substrates to promote physical interactions and the assembly of macromolecular complexes. Here, we discuss the emerging roles of Tudor domain proteins during development, most notably in the Piwi-interacting RNA pathway, but also in other aspects of RNA metabolism, the DNA damage response and chromatin modification.
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